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The Transcription Factor IRF6 Co-Represses PPARγ-Mediated Cytoprotection in Ischemic Cerebrovascular Endothelial Cells

Activation of peroxisome proliferator-activated receptor gamma (PPARγ) in the cerebrovascular endothelium is a key suppressor of post-stroke brain damage. However, the role of PPARγ’s co-regulators during cerebral ischemia remains largely unknown. Here, we show that the transcription factor IRF6 is...

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Detalles Bibliográficos
Autores principales: Huang, Rongzhong, Hu, Zicheng, Feng, Yuxing, Yu, Lehua, Li, Xingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438409/
https://www.ncbi.nlm.nih.gov/pubmed/28526834
http://dx.doi.org/10.1038/s41598-017-02095-3