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Exendin-4 Treatment Improves LPS-Induced Depressive-Like Behavior Without Affecting Pro-Inflammatory Cytokines

Background: Exendin-4 is a peptide agonist of the glucagon-like peptide-1 (GLP-1) receptor, currently in clinical trials as a potential disease-modifying therapy for Parkinson’s disease. In light of this, it is important to understand potential modes of action of exendin-4 in the brain. Exendin-4 is...

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Detalles Bibliográficos
Autores principales: Ventorp, Filip, Bay-Richter, Cecilie, Nagendra, Analise Sauro, Janelidze, Shorena, Matsson, Viktor Sjödahl, Lipton, Jack, Nordström, Ulrika, Westrin, Åsa, Brundin, Patrik, Brundin, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438473/
https://www.ncbi.nlm.nih.gov/pubmed/28387682
http://dx.doi.org/10.3233/JPD-171068