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Reduced HDAC2 in skeletal muscle of COPD patients

BACKGROUND: Skeletal muscle weakness in chronic obstructive pulmonary disease (COPD) is an important predictor of poor prognosis, but the molecular mechanisms of muscle weakness in COPD have not been fully elucidated. The aim of this study was to investigate the role of histone deacetylases(HDAC) in...

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Detalles Bibliográficos
Autores principales: To, Masako, Swallow, Elisabeth B., Akashi, Kenich, Haruki, Kosuke, Natanek, S Amanda, Polkey, Michael I., Ito, Kazuhiro, Barnes, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438490/
https://www.ncbi.nlm.nih.gov/pubmed/28526090
http://dx.doi.org/10.1186/s12931-017-0588-8