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Reduced HDAC2 in skeletal muscle of COPD patients
BACKGROUND: Skeletal muscle weakness in chronic obstructive pulmonary disease (COPD) is an important predictor of poor prognosis, but the molecular mechanisms of muscle weakness in COPD have not been fully elucidated. The aim of this study was to investigate the role of histone deacetylases(HDAC) in...
Autores principales: | To, Masako, Swallow, Elisabeth B., Akashi, Kenich, Haruki, Kosuke, Natanek, S Amanda, Polkey, Michael I., Ito, Kazuhiro, Barnes, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438490/ https://www.ncbi.nlm.nih.gov/pubmed/28526090 http://dx.doi.org/10.1186/s12931-017-0588-8 |
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