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Atorvastatin alters the expression of genes related to bile acid metabolism and circadian clock in livers of mice

AIM: Atorvastatin is a HMG-CoA reductase inhibitor used for hyperlipidemia. Atorvastatin is generally safe but may induce cholestasis. The present study aimed to examine the effects of atorvastatin on hepatic gene expression related to bile acid metabolism and homeostasis, as well as the expression...

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Detalles Bibliográficos
Autores principales: Li, Wen-Kai, Li, Huan, Lu, Yuan-Fu, Li, Ying-Ying, Fu, Zidong Donna, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438592/
https://www.ncbi.nlm.nih.gov/pubmed/28533986
http://dx.doi.org/10.7717/peerj.3348