Maintenance of the marginal zone B cell compartment specifically requires the RNA-binding protein ZFP36L1

RNA binding proteins (RBP) of the ZFP36 family are best known for inhibiting the expression of cytokines through binding to AU rich elements in the 3’UTR and promoting mRNA decay. Here we show an indispensible role for ZFP36L1 as the regulator of a post-transcriptional hub that determined the identi...

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Detalles Bibliográficos
Autores principales: Newman, Rebecca, Ahlfors, Helena, Saveliev, Alexander, Galloway, Alison, Hodson, Daniel J, Williams, Robert, Besra, Gurdyal S., Cook, Charlotte N, Cunningham, Adam F, Bell, Sarah E, Turner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438597/
https://www.ncbi.nlm.nih.gov/pubmed/28394372
http://dx.doi.org/10.1038/ni.3724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438597/
https://www.ncbi.nlm.nih.gov/pubmed/28394372
http://dx.doi.org/10.1038/ni.3724

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