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Maintenance of the marginal zone B cell compartment specifically requires the RNA-binding protein ZFP36L1
RNA binding proteins (RBP) of the ZFP36 family are best known for inhibiting the expression of cytokines through binding to AU rich elements in the 3’UTR and promoting mRNA decay. Here we show an indispensible role for ZFP36L1 as the regulator of a post-transcriptional hub that determined the identi...
Autores principales: | Newman, Rebecca, Ahlfors, Helena, Saveliev, Alexander, Galloway, Alison, Hodson, Daniel J, Williams, Robert, Besra, Gurdyal S., Cook, Charlotte N, Cunningham, Adam F, Bell, Sarah E, Turner, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438597/ https://www.ncbi.nlm.nih.gov/pubmed/28394372 http://dx.doi.org/10.1038/ni.3724 |
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