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Floor plate-derived netrin-1 is dispensable for commissural axon guidance

Netrin-1 is an evolutionarily conserved secreted extracellular matrix protein discovered using genetic and biochemical screens for its role in axon guidance at the central nervous system (CNS) midline1,2. Netrin-1 is expressed by cells localized at CNS midline, such as the floor plate in vertebrate...

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Detalles Bibliográficos
Autores principales: Dominici, Chloé, Moreno-Bravo, Juan Antonio, Puiggros, Sergi Roig, Rappeneau, Quentin, Rama, Nicolas, Vieugue, Pauline, Bernet, Agnes, Mehlen, Patrick, Chédotal, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438598/
https://www.ncbi.nlm.nih.gov/pubmed/28445456
http://dx.doi.org/10.1038/nature22331