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An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cells

Despite great advances in the treatment of acute leukemia, a renaissance of current chemotherapy needs to be improved. The present study elucidates the underlying mechanism of a new synthetic quinoline derivative, MPT0B392 (B392) against acute leukemia and its potential anticancer effect in drug res...

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Detalles Bibliográficos
Autores principales: Chao, Min-Wu, Huang, Han-Li, HuangFu, Wei-Chun, Hsu, Kai-Cheng, Liu, Yi-Min, Wu, Yi-Wen, Lin, Chao-Feng, Chen, Yi-Lin, Lai, Mei-Jung, Lee, Hsueh-Yun, Liou, Jing-Ping, Teng, Che-Ming, Yang, Chia-Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438607/
https://www.ncbi.nlm.nih.gov/pubmed/28186963
http://dx.doi.org/10.18632/oncotarget.15115