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Pygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells

Anti-microtubule drugs, such as paclitaxel (PTX), are extensively used for the treatment of numerous cancers. However, growing evidence has shown that PTX resistance, either intrinsic or acquired, frequently occurs in patients and results in the failure of treatment, contributing to the high cancer...

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Detalles Bibliográficos
Autores principales: Zhou, Cefan, Cheng, Hongxia, Qin, Wenying, Zhang, Yi, Xiong, Hui, Yang, Jing, Huang, Huang, Wang, Yefu, Chen, Xing-Zhen, Tang, Jingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438618/
https://www.ncbi.nlm.nih.gov/pubmed/28427190
http://dx.doi.org/10.18632/oncotarget.15843