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Pygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells
Anti-microtubule drugs, such as paclitaxel (PTX), are extensively used for the treatment of numerous cancers. However, growing evidence has shown that PTX resistance, either intrinsic or acquired, frequently occurs in patients and results in the failure of treatment, contributing to the high cancer...
Autores principales: | Zhou, Cefan, Cheng, Hongxia, Qin, Wenying, Zhang, Yi, Xiong, Hui, Yang, Jing, Huang, Huang, Wang, Yefu, Chen, Xing-Zhen, Tang, Jingfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438618/ https://www.ncbi.nlm.nih.gov/pubmed/28427190 http://dx.doi.org/10.18632/oncotarget.15843 |
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