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DNA methylation directly downregulates human cathelicidin antimicrobial peptide gene (CAMP) promoter activity

LL-37, the active product of human cathelicidin antimicrobial peptide (CAMP) has a broad spectrum of antibacterial activity. LL-37 also has important physiological functions in immune regulation, angiogenesis and in modulating apoptosis. The roles of LL-37 in oral squamous cell carcinoma (OSCC) are...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Qi, Guangying, Qin, Mingqun, Zou, Yantao, Zhong, Kanghua, Tang, Ying, Guo, Yong, Jiang, Xinxiang, Liang, Lihua, Zou, Xianqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438620/
https://www.ncbi.nlm.nih.gov/pubmed/28427192
http://dx.doi.org/10.18632/oncotarget.15847