A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway

Metabolic reprogramming is critical for cancer cell proliferation. Glutaminolysis which provides cancer cells with bioenergetics and intermediates for macromolecular synthesis have been intensively studied in recent years. Glutaminase C (GAC) is the first and rate-limiting enzyme in glutaminolysis a...

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Detalles Bibliográficos
Autores principales: Han, Tianyu, Guo, Meng, Zhang, Tingting, Gan, Mingxi, Xie, Caifeng, Wang, Jian-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438631/
https://www.ncbi.nlm.nih.gov/pubmed/28039459
http://dx.doi.org/10.18632/oncotarget.14188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438631/
https://www.ncbi.nlm.nih.gov/pubmed/28039459
http://dx.doi.org/10.18632/oncotarget.14188

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