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High Myc expression and transcription activity underlies intra-tumoral heterogeneity in triple-negative breast cancer

We have previously identified a novel intra-tumoral dichotomy in triple-negative breast cancer (TNBC) based on the differential responsiveness to a reporter containing the Sox2 regulatory region-2 (SRR2), with reporter responsive (RR) cells being more stem-like than reporter unresponsive (RU) cells....

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Detalles Bibliográficos
Autores principales: Gupta, Nidhi, Jung, Karen, Wu, Chengsheng, Alshareef, Abdulraheem, Alqahtani, Hind, Damaraju, Sambasivarao, Mackey, John R., Ghosh, Sunita, Sabri, Siham, Abdulkarim, Bassam S., Bigras, Gilbert, Lai, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438634/
https://www.ncbi.nlm.nih.gov/pubmed/28427212
http://dx.doi.org/10.18632/oncotarget.15891