Identifying the structure-activity relationship of leelamine necessary for inhibiting intracellular cholesterol transport

Leelamine is an anticancer chemotherapeutic agent inhibiting intracellular cholesterol transport. Cell death mediated by leelamine occurs due to the lysosomotropic property of the compound, its accumulation in the lysosome, and inhibition of cholesterol transport leading to lack of availability for...

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Detalles Bibliográficos
Autores principales: Gowda, Raghavendra, Inamdar, Gajanan S., Kuzu, Omer, Dinavahi, Saketh S., Krzeminski, Jacek, Battu, Madhu Babu, Voleti, Sreedhara R., Amin, Shantu, Robertson, Gavin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438648/
https://www.ncbi.nlm.nih.gov/pubmed/28423677
http://dx.doi.org/10.18632/oncotarget.16002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438648/
https://www.ncbi.nlm.nih.gov/pubmed/28423677
http://dx.doi.org/10.18632/oncotarget.16002

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