Cargando…

Down-regulation of interleukin 7 receptor (IL-7R) contributes to central nervous system demyelination

Interleukin 7 receptor (IL-7R) has been associated with the pathogenesis of multiple sclerosis (MS), though the mechanisms are not clear. Because myelin expression is highly conserved between zebrafish and mammals, zebrafish have become an ideal model for studying demyelination. We used a transgenic...

Descripción completa

Detalles Bibliográficos
Autores principales: Lei, Xudan, Cai, Shijiao, Chen, Yang, Cui, Jianlin, Wang, Yajie, Li, Zongjin, Li, Yuhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438658/
https://www.ncbi.nlm.nih.gov/pubmed/28415697
http://dx.doi.org/10.18632/oncotarget.16081