Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways

Malignant melanoma is the deadliest form of all skin cancers. Itraconazole, a commonly used systemic antifungal drug, has been tested for its anti-tumor effects on basal cell carcinoma, prostate cancer, and non-small cell lung cancer. Whether itraconazole has any specific anti-tumor effect on melano...

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Detalles Bibliográficos
Autores principales: Liang, Guanzhao, Liu, Musang, Wang, Qiong, Shen, Yongnian, Mei, Huan, Li, Dongmei, Liu, Weida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438669/
https://www.ncbi.nlm.nih.gov/pubmed/28212537
http://dx.doi.org/10.18632/oncotarget.15324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438669/
https://www.ncbi.nlm.nih.gov/pubmed/28212537
http://dx.doi.org/10.18632/oncotarget.15324

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