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Expression of HIF-1α in medullary thyroid cancer identifies a subgroup with poor prognosis

BACKGROUND: Medullary thyroid cancer (MTC) comprises only 4% of all thyroid cancers and originates from the parafollicular C-cells. HIF-1α expression has been implied as an indicator of worse prognosis in various solid tumors. However, whether expression of HIF-1α is a prognosticator in MTC remained...

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Detalles Bibliográficos
Autores principales: Lodewijk, Lutske, van Diest, Paul, van der Groep, Petra, ter Hoeve, Natalie, Schepers, Abbey, Morreau, Johannes, Bonenkamp, Johannes, van Engen - van Grunsven, Adriana, Kruijff, Schelto, van Hemel, Bettien, Links, Thera, van Dijkum, Els Nieveen, van Eeden, Susanne, Valk, Gerlof, Rinkes, Inne Borel, Vriens, Menno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438680/
https://www.ncbi.nlm.nih.gov/pubmed/28404916
http://dx.doi.org/10.18632/oncotarget.15622