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Antitumor effects of cyclin dependent kinase 9 inhibition in esophageal adenocarcinoma

Role of cyclin dependent kinase 9(CDK9) as a potential target in esophageal adenocarcinoma (EAC) is unknown. We investigated CDK9 protein expression in EAC and Barrett's esophagus and role of CDK9 in oncogenic processes of EAC in vitro and in murine xenografts. The CDK9 expression was significa...

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Detalles Bibliográficos
Autores principales: Tong, Zhimin, Chatterjee, Devkumar, Deng, Defeng, Veeranki, Omkara, Mejia, Alicia, Ajani, Jaffer A, Hofstetter, Wayne, Lin, Steven, Guha, Sushovan, Kopetz, Scott, Krishnan, Sunil, Maru, Dipen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438684/
https://www.ncbi.nlm.nih.gov/pubmed/28404924
http://dx.doi.org/10.18632/oncotarget.15645