Cargando…
Antitumor effects of cyclin dependent kinase 9 inhibition in esophageal adenocarcinoma
Role of cyclin dependent kinase 9(CDK9) as a potential target in esophageal adenocarcinoma (EAC) is unknown. We investigated CDK9 protein expression in EAC and Barrett's esophagus and role of CDK9 in oncogenic processes of EAC in vitro and in murine xenografts. The CDK9 expression was significa...
Autores principales: | Tong, Zhimin, Chatterjee, Devkumar, Deng, Defeng, Veeranki, Omkara, Mejia, Alicia, Ajani, Jaffer A, Hofstetter, Wayne, Lin, Steven, Guha, Sushovan, Kopetz, Scott, Krishnan, Sunil, Maru, Dipen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438684/ https://www.ncbi.nlm.nih.gov/pubmed/28404924 http://dx.doi.org/10.18632/oncotarget.15645 |
Ejemplares similares
-
Targeting cyclin-dependent kinase 9 by a novel inhibitor enhances radiosensitization and identifies Axl as a novel downstream target in esophageal adenocarcinoma
por: Veeranki, Omkara Lakshmi, et al.
Publicado: (2019) -
Targeting CDK9 and MCL-1 by a new CDK9/p-TEFb inhibitor with and
without 5-fluorouracil in esophageal adenocarcinoma
por: Tong, Zhimin, et al.
Publicado: (2019) -
A novel patient-derived orthotopic xenograft model of esophageal adenocarcinoma provides a platform for translational discoveries
por: Veeranki, Omkara Lakshmi, et al.
Publicado: (2019) -
Taxane-based or platinum-based combination chemotherapy given concurrently with radiation followed by surgery resulting in high cure rates in esophageal cancer patients
por: Lopez, Anthony, et al.
Publicado: (2020) -
Endoscopic management of esophageal cancer
por: Ahmed, Osman, et al.
Publicado: (2019)