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Mechanisms of the anti-tumor activity of Methyl 2-(-5-fluoro-2-hydroxyphenyl)-1 H-benzo[d]imidazole-5-carboxylate against breast cancer in vitro and in vivo

Microtubule Targeting Agents (MTAs) induce cell death through mitotic arrest, preferentially affecting rapidly dividing cancer cells over slowly proliferating normal cells. Previously, we showed that Methyl 2-(−5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) acts as a potential M...

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Detalles Bibliográficos
Autores principales: Hasanpourghadi, Mohadeseh, Pandurangan, Ashok Kumar, Karthikeyan, Chandrabose, Trivedi, Piyush, Mustafa, Mohd Rais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438696/
https://www.ncbi.nlm.nih.gov/pubmed/28392503
http://dx.doi.org/10.18632/oncotarget.16263