IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway

PURPOSE: Numerous studies have reported that glioma patients with isocitrate dehydrogenase 1(IDH1) R132H mutation are sensitive to temozolomide treatment. However, the mechanism of IDH1 mutations on the chemosensitivity of glioma remains unclear. In this study, we investigated the role and the poten...

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Detalles Bibliográficos
Autores principales: Li, Kaishu, Ouyang, Leping, He, Mingliang, Luo, Ming, Cai, Wangqing, Tu, Yalin, Pi, Rongbiao, Liu, Anmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438698/
https://www.ncbi.nlm.nih.gov/pubmed/28427200
http://dx.doi.org/10.18632/oncotarget.15868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438698/
https://www.ncbi.nlm.nih.gov/pubmed/28427200
http://dx.doi.org/10.18632/oncotarget.15868

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