Stellettin B induces apoptosis in human chronic myeloid leukemia cells via targeting PI3K and Stat5

Novel agents are still urgently expected for therapy of chronic myeloid leukemia (CML). The in vitro anti-leukemia activity of Stellettin B (Stel B), a triterpenoid we isolated from marine sponge Jaspis stellifera, on human CML K562 and KU812 cells was recently investigated. Stel B inhibited K562 an...

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Detalles Bibliográficos
Autores principales: Chen, Yali, Zhou, Qianxiang, Zhang, Lei, Zhong, Yuxu, Fan, Guanwei, Zhang, Zhe, Wang, Ran, Jin, Meihua, Qiu, Yuling, Kong, Dexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438702/
https://www.ncbi.nlm.nih.gov/pubmed/28423649
http://dx.doi.org/10.18632/oncotarget.15957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438702/
https://www.ncbi.nlm.nih.gov/pubmed/28423649
http://dx.doi.org/10.18632/oncotarget.15957

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