NDRG2 promotes adriamycin sensitivity through a Bad/p53 complex at the mitochondria in breast cancer

Chemo-resistance presents a difficult challenge for the treatment of breast cancer. Our previous study showed that N-Myc downstream-regulated gene 2 (NDRG2) is involved in p53-mediated apoptosis induced by chemotherapy, through a mechanism that has so far remained obscure. Here, we explored the role...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Yifang, Yu, Shentong, Zhang, Yongping, Zhang, Yuan, Zhao, Huadong, Xiao, Zhixiong, Yao, Libo, Chen, Suning, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438710/
https://www.ncbi.nlm.nih.gov/pubmed/28423695
http://dx.doi.org/10.18632/oncotarget.16035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438710/
https://www.ncbi.nlm.nih.gov/pubmed/28423695
http://dx.doi.org/10.18632/oncotarget.16035

Ejemplares similares