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NDRG2 promotes adriamycin sensitivity through a Bad/p53 complex at the mitochondria in breast cancer
Chemo-resistance presents a difficult challenge for the treatment of breast cancer. Our previous study showed that N-Myc downstream-regulated gene 2 (NDRG2) is involved in p53-mediated apoptosis induced by chemotherapy, through a mechanism that has so far remained obscure. Here, we explored the role...
Autores principales: | Wei, Yifang, Yu, Shentong, Zhang, Yongping, Zhang, Yuan, Zhao, Huadong, Xiao, Zhixiong, Yao, Libo, Chen, Suning, Zhang, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438710/ https://www.ncbi.nlm.nih.gov/pubmed/28423695 http://dx.doi.org/10.18632/oncotarget.16035 |
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