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A novel bispecific c-MET/PD-1 antibody with therapeutic potential in solid cancer

The bispecific antibody is a novel antibody, which can target two different antigens and mediate specific killing effects by selectively redirecting effector cells to the target cells. Here, we designed and synthesized a bispecific antibody (BsAb) that can bind cellular-mesenchymal to epithelial tra...

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Detalles Bibliográficos
Autores principales: Sun, Zu-Jun, Wu, Yi, Hou, Wei-Hua, Wang, Yu-Xiong, Yuan, Qing-Yun, Wang, Hui-Jie, Yu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438713/
https://www.ncbi.nlm.nih.gov/pubmed/28404966
http://dx.doi.org/10.18632/oncotarget.16173