Targeting the overexpressed ROC1 induces G2 cell cycle arrest and apoptosis in esophageal cancer cells

Recent reports showed that regulator of Cullins-1 (ROC1) play an important role in tumor progression in a tumor-specific manner. However, the role and mechanism of ROC1 in esophageal cancer remains elusive. Here we demonstrated that ROC1 was overexpressed in esophageal squamous cell carcinomas, whic...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jingyang, Li, Shuo, Shang, Zhaoyang, Lin, Shan, Gao, Peng, Zhang, Yi, Hou, Shuaiheng, Mo, Saijun, Cao, Wenbo, Dong, Ziming, Hu, Tao, Chen, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438718/
https://www.ncbi.nlm.nih.gov/pubmed/28418860
http://dx.doi.org/10.18632/oncotarget.16250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438718/
https://www.ncbi.nlm.nih.gov/pubmed/28418860
http://dx.doi.org/10.18632/oncotarget.16250

Ejemplares similares