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Targeting the overexpressed ROC1 induces G2 cell cycle arrest and apoptosis in esophageal cancer cells
Recent reports showed that regulator of Cullins-1 (ROC1) play an important role in tumor progression in a tumor-specific manner. However, the role and mechanism of ROC1 in esophageal cancer remains elusive. Here we demonstrated that ROC1 was overexpressed in esophageal squamous cell carcinomas, whic...
Autores principales: | Zhang, Jingyang, Li, Shuo, Shang, Zhaoyang, Lin, Shan, Gao, Peng, Zhang, Yi, Hou, Shuaiheng, Mo, Saijun, Cao, Wenbo, Dong, Ziming, Hu, Tao, Chen, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438718/ https://www.ncbi.nlm.nih.gov/pubmed/28418860 http://dx.doi.org/10.18632/oncotarget.16250 |
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