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Sex Differences in the Blood Concentration of Tacrolimus in Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients with CYP3A5*3/*3

The purpose of this study was to describe the impact of sex and cytochrome P450 3A5 (CYP3A5) variant on the blood concentration of tacrolimus in patients with systemic lupus erythematosus or rheumatoid arthritis. The blood concentration of tacrolimus (ng/mL) divided by the daily dose of tacrolimus (...

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Detalles Bibliográficos
Autores principales: Ito, Ayano, Okada, Yuko, Hashita, Tadahiro, Aomori, Tohru, Hiromura, Keiju, Nojima, Yoshihisa, Nakamura, Tomonori, Araki, Takuya, Yamamoto, Koujirou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438821/
https://www.ncbi.nlm.nih.gov/pubmed/28324194
http://dx.doi.org/10.1007/s10528-017-9795-8