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Gene expression levels of gamma-glutamyl hydrolase in tumor tissues may be a useful biomarker for the proper use of S-1 and tegafur-uracil/leucovorin in preoperative chemoradiotherapy for patients with rectal cancer

PURPOSE: Preoperative chemoradiotherapy (CRT) using 5-fluorouracil (5-FU)-based chemotherapy is the standard of care for rectal cancer. The effect of additional chemotherapy during the period between the completion of radiotherapy and surgery remains unclear. Predictive factors for CRT may differ be...

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Detalles Bibliográficos
Autores principales: Sadahiro, Sotaro, Suzuki, T., Tanaka, A., Okada, K., Saito, G., Miyakita, H., Ogimi, T., Nagase, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438825/
https://www.ncbi.nlm.nih.gov/pubmed/28417167
http://dx.doi.org/10.1007/s00280-017-3295-8