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Presence of new mutations in the TP53 gene in patients with low-risk myelodysplastic syndrome: two case reports

BACKGROUND: Myelodysplastic syndromes are heterogeneous disorders. Patients with myelodysplastic syndrome disease often have ineffective hematopoiesis, cytopenias, blood cell dysplasia in one or more cell types, and are at high risk for developing acute myeloid leukemia. In myelodysplastic syndrome,...

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Detalles Bibliográficos
Autores principales: Duarte, Fernando Barroso, Lemes, Romélia Pinheiro Gonçalves, dos Santos, Talyta Ellen de Jesus, Barbosa, Maritza Cavalcante, de Vasconcelos, João Paulo Leitão, Rocha-Filho, Francisco Dário, Zalcberg, Ilana, Coutinho, Diego, Figueiredo, Monalisa Feliciano, Carlos, Luciana Barros, de Vasconcelos, Paulo Roberto Leitão
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438849/
https://www.ncbi.nlm.nih.gov/pubmed/28527473
http://dx.doi.org/10.1186/s13256-017-1301-8