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Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases

In 2002, intracellular protein complexes known as the inflammasomes were discovered and were shown to have a crucial role in the sensing of intracellular pathogen- and danger-associated molecular patterns (PAMPs and DAMPs). Activation of the inflammasomes results in the processing and subsequent sec...

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Detalles Bibliográficos
Autores principales: Fenini, Gabriele, Contassot, Emmanuel, French, Lars E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438978/
https://www.ncbi.nlm.nih.gov/pubmed/28588486
http://dx.doi.org/10.3389/fphar.2017.00278