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AGO2 Negatively Regulates Type I Interferon Signaling Pathway by Competition Binding IRF3 with CBP/p300

Viral infection triggers a series of signaling cascades and host innate immune responses, including interferon (IFN) production, which depends on coordinated activity of multiple transcription factors. IFN regulatory factor 3 (IRF3) and transcriptional coactivator CREB binding protein (CBP) and/or p...

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Detalles Bibliográficos
Autores principales: Wang, Shengyu, Sun, Xin, Yi, Chenyang, Zhang, Dan, Lin, Xian, Sun, Xiaomei, Chen, Huanchun, Jin, Meilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438986/
https://www.ncbi.nlm.nih.gov/pubmed/28589097
http://dx.doi.org/10.3389/fcimb.2017.00195