Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB

The serpinopathies are human pathologies caused by mutations that promote polymerisation and intracellular deposition of proteins of the serpin superfamily, leading to a poorly understood cell toxicity. The dementia FENIB is caused by polymerisation of the neuronal serpin neuroserpin (NS) within the...

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Detalles Bibliográficos
Autores principales: Guadagno, Noemi A., Moriconi, Claudia, Licursi, Valerio, D'Acunto, Emanuela, Nisi, Paola S., Carucci, Nicoletta, De Jaco, Antonella, Cacci, Emanuele, Negri, Rodolfo, Lupo, Giuseppe, Miranda, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439028/
https://www.ncbi.nlm.nih.gov/pubmed/28363799
http://dx.doi.org/10.1016/j.nbd.2017.03.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439028/
https://www.ncbi.nlm.nih.gov/pubmed/28363799
http://dx.doi.org/10.1016/j.nbd.2017.03.010

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