Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model

BACKGROUND. To expedite the evaluation of vaccines against paratyphoid fever, we aimed to develop the first human challenge model of Salmonella enterica serovar Paratyphi A infection. METHODS. Two groups of 20 participants underwent oral challenge with S. Paratyphi A following sodium bicarbonate pre...

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Detalles Bibliográficos
Autores principales: Dobinson, Hazel C., Gibani, Malick M., Jones, Claire, Thomaides-Brears, Helena B., Voysey, Merryn, Darton, Thomas C., Waddington, Claire S., Campbell, Danielle, Milligan, Iain, Zhou, Liqing, Shrestha, Sonu, Kerridge, Simon A., Peters, Anna, Stevens, Zoe, Podda, Audino, Martin, Laura B., D’Alessio, Flavia, Thanh, Duy Pham, Basnyat, Buddha, Baker, Stephen, Angus, Brian, Levine, Myron M., Blohmke, Christoph J., Pollard, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439345/
https://www.ncbi.nlm.nih.gov/pubmed/28158395
http://dx.doi.org/10.1093/cid/cix042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439345/
https://www.ncbi.nlm.nih.gov/pubmed/28158395
http://dx.doi.org/10.1093/cid/cix042

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