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Mdm proteins: critical regulators of embryogenesis and homoeostasis
Mdm2 and Mdm4 are negative regulators of the tumour suppressor p53; hence, this relationship is the focus of many cancer-related studies. A multitude of experiments across various developmental stages have been conducted to explore the tissue-specific roles of these proteins in the mouse. When Mdm2...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439424/ https://www.ncbi.nlm.nih.gov/pubmed/28093454 http://dx.doi.org/10.1093/jmcb/mjx004 |