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Mdm proteins: critical regulators of embryogenesis and homoeostasis

Mdm2 and Mdm4 are negative regulators of the tumour suppressor p53; hence, this relationship is the focus of many cancer-related studies. A multitude of experiments across various developmental stages have been conducted to explore the tissue-specific roles of these proteins in the mouse. When Mdm2...

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Detalles Bibliográficos
Autores principales: Moyer, Sydney M., Larsson, Connie A., Lozano, Guillermina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439424/
https://www.ncbi.nlm.nih.gov/pubmed/28093454
http://dx.doi.org/10.1093/jmcb/mjx004