Topological defects in epithelia govern cell death and extrusion

Epithelia remove excess cells through extrusion, and prevent accumulation of unnecessary or pathological cells. The extrusion process can be triggered by apoptotic signaling1, oncogenic transformation2,3, and overcrowding of cells4–6. Despite the important links of cell extrusion to developmental7,...

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Detalles Bibliográficos
Autores principales: Saw, Thuan Beng, Doostmohammadi, Amin, Nier, Vincent, Kocgozlu, Leyla, Thampi, Sumesh, Toyama, Yusuke, Marcq, Philippe, Lim, Chwee Teck, Yeomans, Julia M, Ladoux, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439518/
https://www.ncbi.nlm.nih.gov/pubmed/28406198
http://dx.doi.org/10.1038/nature21718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439518/
https://www.ncbi.nlm.nih.gov/pubmed/28406198
http://dx.doi.org/10.1038/nature21718

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