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Exogenous expression of Drp1 plays neuroprotective roles in the Alzheimer's disease in the Aβ42 transgenic Drosophila model

BACKGROUND: Alzheimer's disease (AD) is one of the most common neurodegenerative disorders. Recent studies have shown that mitochondrial dysfunction is a causative factor of AD. Drp1 (Dynamin-related protein 1), a regulator of mitochondrial fission, shows neuroprotective effects on Parkinson’s...

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Detalles Bibliográficos
Autores principales: Lv, Fengshou, Yang, Xiaopeng, Cui, Chuanju, Su, Chunhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439651/
https://www.ncbi.nlm.nih.gov/pubmed/28531191
http://dx.doi.org/10.1371/journal.pone.0176183