Autophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer

Epidermal growth factor receptor (EGFR) is over-expressed in about 50% of Triple negative breast cancers (TNBCs), but EGFR inhibitors have not been effective in treating TNBC patients. Increasing evidence supports that autophagy was related to drug resistance at present. However, the role and the me...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoyun, He, Kewen, Ma, Qinghua, Yu, Qian, Liu, Chenyu, Ndege, Isabella, Wang, Xinzhao, Yu, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439698/
https://www.ncbi.nlm.nih.gov/pubmed/28531218
http://dx.doi.org/10.1371/journal.pone.0177694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439698/
https://www.ncbi.nlm.nih.gov/pubmed/28531218
http://dx.doi.org/10.1371/journal.pone.0177694

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