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Autophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer
Epidermal growth factor receptor (EGFR) is over-expressed in about 50% of Triple negative breast cancers (TNBCs), but EGFR inhibitors have not been effective in treating TNBC patients. Increasing evidence supports that autophagy was related to drug resistance at present. However, the role and the me...
Autores principales: | Liu, Zhaoyun, He, Kewen, Ma, Qinghua, Yu, Qian, Liu, Chenyu, Ndege, Isabella, Wang, Xinzhao, Yu, Zhiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439698/ https://www.ncbi.nlm.nih.gov/pubmed/28531218 http://dx.doi.org/10.1371/journal.pone.0177694 |
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