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Psychosine enhances the shedding of membrane microvesicles: Implications in demyelination in Krabbe’s disease

In prior studies, our laboratory showed that psychosine accumulates and disrupts lipid rafts in brain membranes of Krabbe’s disease. A model of lipid raft disruption helped explaining psychosine’s effects on several signaling pathways important for oligodendrocyte survival and differentiation but pr...

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Detalles Bibliográficos
Autores principales: D’Auria, Ludovic, Reiter, Cory, Ward, Emma, Moyano, Ana Lis, Marshall, Michael S., Nguyen, Duc, Scesa, Giuseppe, Hauck, Zane, van Breemen, Richard, Givogri, Maria I., Bongarzone, Ernesto R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439731/
https://www.ncbi.nlm.nih.gov/pubmed/28531236
http://dx.doi.org/10.1371/journal.pone.0178103