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Psychosine enhances the shedding of membrane microvesicles: Implications in demyelination in Krabbe’s disease
In prior studies, our laboratory showed that psychosine accumulates and disrupts lipid rafts in brain membranes of Krabbe’s disease. A model of lipid raft disruption helped explaining psychosine’s effects on several signaling pathways important for oligodendrocyte survival and differentiation but pr...
Autores principales: | D’Auria, Ludovic, Reiter, Cory, Ward, Emma, Moyano, Ana Lis, Marshall, Michael S., Nguyen, Duc, Scesa, Giuseppe, Hauck, Zane, van Breemen, Richard, Givogri, Maria I., Bongarzone, Ernesto R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439731/ https://www.ncbi.nlm.nih.gov/pubmed/28531236 http://dx.doi.org/10.1371/journal.pone.0178103 |
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