Fluvastatin inhibits AGE-induced cell proliferation and migration via an ERK5-dependent Nrf2 pathway in vascular smooth muscle cells

Advanced glycation endproduct (AGE)-induced vascular smooth muscle cell (VSMC) proliferation and reactive oxygen species (ROS) production are emerging as important mechanisms of diabetic vasculopathy, but little is known about the molecular mechanism responsible for the antioxidative effects of stat...

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Detalles Bibliográficos
Autores principales: Hwang, Ae-Rang, Han, Jung-Hwa, Lim, Jae Hyang, Kang, Young Jin, Woo, Chang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439952/
https://www.ncbi.nlm.nih.gov/pubmed/28542559
http://dx.doi.org/10.1371/journal.pone.0178278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439952/
https://www.ncbi.nlm.nih.gov/pubmed/28542559
http://dx.doi.org/10.1371/journal.pone.0178278

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