Relationships between Poly(ethylene glycol) Modifications on RNA–Spherical Nucleic Acid Conjugates and Cellular Uptake and Circulation Time

[Image: see text] Two synthetic approaches that allow one to control PEG content within spherical nucleic acids (SNAs) have been developed. One approach begins with RNA-modified gold nanoparticles followed by a backfill of PEG 2K alkanethiols, and the other involves co-adsorption of the two entities...

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Detalles Bibliográficos
Autores principales: Chinen, Alyssa B., Ferrer, Jennifer R., Merkel, Timothy J., Mirkin, Chad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439959/
https://www.ncbi.nlm.nih.gov/pubmed/27762539
http://dx.doi.org/10.1021/acs.bioconjchem.6b00483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439959/
https://www.ncbi.nlm.nih.gov/pubmed/27762539
http://dx.doi.org/10.1021/acs.bioconjchem.6b00483

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