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Relationships between Poly(ethylene glycol) Modifications on RNA–Spherical Nucleic Acid Conjugates and Cellular Uptake and Circulation Time

[Image: see text] Two synthetic approaches that allow one to control PEG content within spherical nucleic acids (SNAs) have been developed. One approach begins with RNA-modified gold nanoparticles followed by a backfill of PEG 2K alkanethiols, and the other involves co-adsorption of the two entities...

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Detalles Bibliográficos
Autores principales:	Chinen, Alyssa B., Ferrer, Jennifer R., Merkel, Timothy J., Mirkin, Chad A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2016
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439959/ https://www.ncbi.nlm.nih.gov/pubmed/27762539 http://dx.doi.org/10.1021/acs.bioconjchem.6b00483

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