10-Hydroxycamptothecin (HCPT) nanosuspensions stabilized by mPEG(1000)-HCPT conjugate: high stabilizing efficiency and improved antitumor efficacy

In this study, polyethylene glycol (PEG)ylated 10-hydroxycamptothecin (mPEG(1000)-HCPT) was synthesized and used as a stabilizer to prepare 10-hydroxycamptothecin (HCPT) nanosuspensions for their in vitro and in vivo antitumor investigation. The resultant HCPT nanosuspensions (HCPT-NSps) had a very...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Linjie, Hong, Jingyi, Di, Jing, Guo, Yifei, Han, Meihua, Liu, Meifeng, Wang, Xiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439984/
https://www.ncbi.nlm.nih.gov/pubmed/28553107
http://dx.doi.org/10.2147/IJN.S134005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439984/
https://www.ncbi.nlm.nih.gov/pubmed/28553107
http://dx.doi.org/10.2147/IJN.S134005

Ejemplares similares