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10-Hydroxycamptothecin (HCPT) nanosuspensions stabilized by mPEG(1000)-HCPT conjugate: high stabilizing efficiency and improved antitumor efficacy

In this study, polyethylene glycol (PEG)ylated 10-hydroxycamptothecin (mPEG(1000)-HCPT) was synthesized and used as a stabilizer to prepare 10-hydroxycamptothecin (HCPT) nanosuspensions for their in vitro and in vivo antitumor investigation. The resultant HCPT nanosuspensions (HCPT-NSps) had a very...

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Detalles Bibliográficos
Autores principales:	Yang, Linjie, Hong, Jingyi, Di, Jing, Guo, Yifei, Han, Meihua, Liu, Meifeng, Wang, Xiangtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439984/ https://www.ncbi.nlm.nih.gov/pubmed/28553107 http://dx.doi.org/10.2147/IJN.S134005

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