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The effect of COPD severity and study duration on exacerbation outcome in randomized controlled trials

BACKGROUND: When discontinuation in COPD randomized controlled trials (RCTs) is unevenly distributed between treatments (differential dropout), the capacity to demonstrate treatment effects may be reduced. We investigated the impact of the time of differential dropout on exacerbation outcomes in RCT...

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Detalles Bibliográficos
Autores principales: Eriksson, Göran, Calverley, Peter M, Jenkins, Christine R, Anzueto, Antonio R, Make, Barry J, Lindberg, Magnus, Fagerås, Malin, Postma, Dirkje S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440002/
https://www.ncbi.nlm.nih.gov/pubmed/28553098
http://dx.doi.org/10.2147/COPD.S130713