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The effect of COPD severity and study duration on exacerbation outcome in randomized controlled trials
BACKGROUND: When discontinuation in COPD randomized controlled trials (RCTs) is unevenly distributed between treatments (differential dropout), the capacity to demonstrate treatment effects may be reduced. We investigated the impact of the time of differential dropout on exacerbation outcomes in RCT...
Autores principales: | Eriksson, Göran, Calverley, Peter M, Jenkins, Christine R, Anzueto, Antonio R, Make, Barry J, Lindberg, Magnus, Fagerås, Malin, Postma, Dirkje S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440002/ https://www.ncbi.nlm.nih.gov/pubmed/28553098 http://dx.doi.org/10.2147/COPD.S130713 |
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