Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is an early-onset neurodegenerative disorder. In 2007, a novel locus, SAX2, which is located on chromosome 17p13 and contains 3 genes, ankyrin repeat and FYVE domain-containing 1 (ANKFY1), β-arrestin 2 (ARRB2) and kinesin family memb...

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Detalles Bibliográficos
Autores principales: Ding, Man, Weng, Chao, Fan, Shanghua, Cao, Qian, Lu, Zuneng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440006/
https://www.ncbi.nlm.nih.gov/pubmed/28588446
http://dx.doi.org/10.3389/fnmol.2017.00121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440006/
https://www.ncbi.nlm.nih.gov/pubmed/28588446
http://dx.doi.org/10.3389/fnmol.2017.00121

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